The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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Author information Article notes Copyright and License information Disclaimer. However, chondrosarcoma characteristically shows fragments of hyaline cartilage and cells sitting in the chondrob,astoma. Report of two cases diagnosed by cytology.

Case Report: Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

The histogenesis of chondroblastomas is controversial, although cartilage stem cells or epiphyseal cartilage cells are presumed to be the cells of origin. Chodroid matrix and chicken-wire pattern of calcification is often not seen on FNA and rarely described as a cytology feature of this tumour. Curettings comprised of friable, red-brown soft tissue masses with a gritty feeling on cutting. Clinically, CMF generally has a typical presentation.

Chondrlblastoma cytology, other giant cell-rich tumors and tumorlike lesions such as aneurysmal bone cyst ABCgiant cell tumor, and chondromyxoid fibroma fall under the differential diagnosis of chondroblastoma.

A report of two cases with brief review of pitfalls. Benign cartilaginous tumors almost always appear benign on radiology with sharp circumscribed borders, intact overlying periosteum and no adjacent soft tissue swelling. Various investigations like routine blood and urine examination, serum cyhology and alkaline phosphatase, cytoogy calcium and phosphorus were within normal limits. Back to cited text no. Previous reports have suggested that the cytological features of CMF are distinctive enough to make a confident pre-operative diagnosis on FNAC after clinico-radiological correlation.


Patella, pelvis, fibula, small bones of hands and feet, ribs, skull, mandible, maxillae, vertebrae, scapulae and sternum are considered as atypical localizations. Thin network chicken-wire like to dense obvious deposits of calcification was evident.

Schajowicz F, Gallardo H. A case report and review of literature.

There was cortical destruction with extra-osseous extension of abnormal marrow signals abutting soft tissue and musculature namely peroneal, extensor digitorum longus, flexor hallucis longus, tibialis anterior and posterior, and soleus muscle. Sterling G, Wilson A. Atlas of tumor pathology, second series, fascicle 5. Jaffe HL, Lichtenstein L. The overall cytological features of chondroblastoma are very much characteristic which helps in diagnosing this tumour with a high degree of precision on fine-needle aspiration FNA.

Fine needle aspiration cytology of chondroblastoma of the fibula

Simple curettage with bone grafting chondroblastom the mode of treatment. Various investigations like routine blood and urine examination, serum acid and alkaline phosphatase, serum calcium and phosphorus were within normal limits. A study of cases. Cytological findings of CMF have appeared in only a few reports so far.

It usually affects the young with a peak incidence in the second and third decades of life and a slight male preponderance. Nil Conflict of Interest: Abstract Chondroblastoma is a rare, giant cell-rich, benign neoplasm of bone. Here, we report cytomorphology in two cases of chondroblastoma confirmed by histopathology with a brief review of literature.


Use of fine-needle aspiration biopsy and potential diagnostic pitfalls. J Oral Maxillofac Surg ; A reinterpretation of the so-called calcifying or chondromatous giant cell tumor.

Tumors of bone and cartilage.

The nuclei of the chondroblasts are round-to-ovoid, sometimes bean-shaped, and nuclear folding often causes nuclear grooves to be identified. Metastases are unusual but occur in the lungs at the time of recurrence. Fine-needle cytloogy cytology of chondromyxoid fibroma: Due chondroglastoma the difference in the treatment protocol and prognosis, preoperative diagnosis is mandatory.

Since the past few decades fine needle aspiration cytology FNAC has gained momentum in preoperative diagnosis of bone lesions. Provenance and peer review: Epiphysial chondroblastoma of bone. Ipsilateral inguinal lymphadenopathy was not demonstrable.

On examination, the patient had restricted left knee joint movements with tenderness.

Pathology Outlines – Chondroblastoma

Tibia and femur were normal [ Figure 1 ]. FNA is fast gaining acceptance as an accurate and rapid technique for diagnosing osseous neoplasms.

Benign and malignant cartilage tumors of bone and joint: The radiographical findings in both the cases were also suggestive of benign lesions. Chonrdoblastoma chondroblastoma of bone.