The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Lea and Febiger; Bioavailability of salbutamol sulphate from different suppository formulations.

Optimization of chlorphenesin emulgel formulation

Stability vormulation showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months. As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since ofrmulation showed the highest drug release and smulgel activity.


Analysis of data on the medicament release from ointments. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Blackwell Scientific Publications; Encyclopedia of Pharmaceutical Technology.

Formulation and stability of chloramphenicol gel and emulgel. Marcel Dekker Inc; The Complete Drug Reference.

Medical Applications of Controlled Release. Transdermal controlled release systems.

The Theory and Practice of Industrial Pharmacy. Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: The Pharmaceutical Press; Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.

It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent.

Published online Sep 1. Support Center Support Center. Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.

National Center for Biotechnology InformationU. Az J Pharm Sci. Swarbrick J, Boylan JC, editors.


Formulation and evaluation of topical preparations containing phenol and local vesicants. A study of shear and compression deformations on hydrophilic gels of tretinoin. Please review our privacy policy. They also exhibited higher drug release and antifungal activity than emulel CHL powder.

The drug release from all the emulgels was found to follow diffusion-controlled mechanism. Commercially available CHL topical powder was used for comparison.

Optimization of chlorphenesin emulgel formulation

Formukation the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. Egypt J Pharm Sci.

formulaion Received Dec 31; Accepted May This article has been cited by other articles in PMC. Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium.