Evaluation of the Abbott RealTime HBV DNA Assay and Comparison to the Cobas AmpliPrep/Cobas TaqMan 48 Assay in Monitoring Patients with Chronic. This study is aimed to investigate whether there is drug-resistant strains related detection difference between Abbott RealTime HBV (RealTime). Korean J Lab Med. Apr;28(2) doi: /kjlm [ Performance evaluation of Abbott RealTime HBV Quantification Kit for HBV viral.

Author: Akizragore Moogushakar
Country: Philippines
Language: English (Spanish)
Genre: Education
Published (Last): 15 June 2005
Pages: 154
PDF File Size: 8.16 Mb
ePub File Size: 14.46 Mb
ISBN: 201-4-46856-543-8
Downloads: 5858
Price: Free* [*Free Regsitration Required]
Uploader: Gorisar

The realtimr and reproducibility of the results, along with the automation, fulfilled the quality requirements for implementation of the Abbott RealTime CMV assay in clinical settings. However currently available methods, based on different technologies, show great variation in detection limit and input plasma volume, and generally suffer from lack of standardization.

To study a convenience sample representing ca. Hepatitis-causing viruses initiate significant morbidity and mortality by hvb both acute and chronic infections, and several of these viruses are specifically associated with the development of hepatocellular carcinoma HCC.

Real-Time Hepatitis B Virus Assay

Skip to search form Skip to main content. For Reaptime, please e-mail: Conclusions Special preventive measures universal precaution and vaccinationwhich are fundamental way to protect HCW against HBV infection should be adopted. Extensive survey of HBV integrations facilitates and improves the understanding of the timing and biology of HBV integration during infection and HBV -related hepatocarcinogenesis. The ARCHITECT assay uses a whole blood specimen, a pretreatment step with organic reagents to precipitate proteins and extract the drug, followed by a 2-step automated immunoassay with magnetic microparticles coated with anti-CsA antibody and an acridinium-CsA tracer.


Sequencing analysis was used as the reference method. Genotypes obtained from sequence data were determined using a laboratory-developed HCV sequence analysis tool and the NCBI non-redundant database.

Abbott RealTime HBV assay – Product Profile – BioCentury – BCIQ

Background Hepatitis B Virus HBV may progress to serious consequences and increase dramatically beyond endemic dimensions that transmits to or nbv health care workers HCWs during routine investigation in their work places. Specimen Search for additional papers on this topic. Accurate in situ diagnostic tests play a key role in patient management and control of most infectious diseases.

Liver Rapid Reference Set Application: Efforts to standardize anti-HBs assay methods are expected to share international evidence about the HBV infection-preventing strategy. Despite the availability of gealtime effective vaccine against hepatitis B virus HBVchronic infection with the virus remains a major global health concern.

Furthermore, a cirrhosis-dependent HBV integration pattern is observed, affecting distinct targeted genes. A total of serum samples realrime patients with hepatitis B were tested.

Quantitation of cytomegalovirus CMV viral load in the transplant patients has become a standard practice for monitoring the response to antiviral therapy. Aptima demonstrated excellent precision, linearity, and accuracy in all genotypes tested.

The limit of detection of the assay was estimated to be 4. The performance of Abbott RealTime HBV Quantification kit was excellent; thus, it should be widely used in starting and monitoring of antiviral therapy in Korean patients with chronic hepatitis B.


Abbott RealTime HBV Assay

It is also being investigated for the potential treatment of coronary heart disease. Analysis of paired assay results below and above each assay’s limit of quantification LOQ indicated that a significantly P Abbott assay LOQ but above realtims Chiron assay LOQ, indicating that the Chiron assay is significantly more sensitive than the Abbott assay. Renal manifestations of chronic HBV infection are usually glomerular.

Reaptime treatment slowed down the progression of his renal disease.

Further larger scale studies are required to determine the significance of newly detected mutations. Viral hepatitis is a significant disease afflicting hundreds of millions of people. Rhoads and Thomas P.

Therapeutic vaccines in HBV: The overall prevalence in female subjects was 8. Population dynamics indicated that HBV -D7 epidemic in Tunisia grew exponentially from s to s.

Abbott ‘s oncology research programs are focused on pioneering trageted, less toxic therapies, aimed at different aspects of tumor growth and development. This would involve simultaneous targeting of multiple regions of the genome, or regions in which variation or reaktime is not tolerated.